Module 2: Drug Profile activities
Section 3: Signal Transduction Mechanisms for Receptors
For your chosen drug:
1. Describe the mechanism of action. Your answer should:
1. Identify how the interaction of the drug with its molecular target(s) accounts for the major therapeutic effect (i.e. the effect you want the drug to cause in clinical practice; e.g. for paracetamol – pain relief)
2. Include a description of how the drug alters function at the cellular level.
3. Include a description of how the altered cellular function manifests as a change in body system function, and the eventual major therapeutic response
Critically review 2 ORIGINAL RESEARCH PEER REVIEWED journal articles that provide evidence for the clinical effectiveness of your drug IN HUMANS. Your response should identify and critique the:
0. Type of study (e.g. randomised control trial, anecdotal report, etc).
1. Comparator agent (e.g. placebo, current gold standard therapy, etc).
2. Sample size (the number of study participants).
3. Measures of effectiveness.
On the basis of this critique, briefly summarise your interpretation of the evidence for the effectiveness of your drug.